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Medication Therapy for Treatment of Thalassemias

Thalassemia disease is a group of inherited autosomal recessive blood disorders, in which the body makes an abnormal form of hemoglobin, the protein in red blood cells that carries oxygen thus causing anemia, the characteristic presenting symptom of the thalassemias. Patient with thalassemia will get regular blood transfusion to treat his anemia, These transfusions can lead to a build-up of iron which can be harmful and this can cause serious side effects including diabetes, heart failure and liver disease.

The iron overload related to thalassemia may be treated by chelation therapy with medications such as Desferrioxamine, Deferiprone or Deferasirox. Medications therapy in thalassemia can be used to remove excess iron from the blood, This may have severe side effects and must be carefully monitored.

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Treatment For Thalassemia by Bone Marrow Transplant

The Bone Marrow Transplantation (BMT) Service is a medical treatment that dedicated to providing exceptional patient care and novel treatment options for patients with malignant and benign diseases of the blood-building system who require an autologous or allogeneic transplant. The BMT are common procedures for treatment of Thalassemia. A bone marrow transplant is a procedure to replace damaged or destroyed bone marrow with healthy bone marrow stem cells.

Bone marrow is found inside the bones and is the origination of stem cells that create red blood cells, white blood cells, and platelets. Stem cells are immature cells in the bone marrow that give rise to all of your blood cells. There are two types of Bone Marrow Transplants; Autologous bone marrow transplant and Allogenic bone marrow transplant.

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Treatment For Thalassemia by Hematopoietic Stem Cell Transplant

A stem cell transplant is the only treatment that can cure thalassemia, this treatment is to replace or to repair a patient’s cells or tissues that are damaged with healthy ones from another person (a donor). For patients who do not have such a donor in the family, an unrelated volunteer donor can be used. Stem cells are the cells inside bone marrow that make red blood cells and other types of blood cells. Stem cells have the remarkable potential to develop into many different cell types in the body.

Hematopoietic stem cell transplantation (HSCT) has become an accepted method of therapy for the treatment of thalassemia, by stem cell transplantation is the basis of treatment that is being studied in the last two decades due to improvements in preventive strategies, and effective control of transplant-related complications. The rate of rejection/thalassemia recurrence was much higher in thalassemic patients than in patients transplanted because of malignancies.

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Treatment For Thalassemia By Regular Blood Transfusions

Thalassemia Disease is a genetic blood disorder that affects the production of the hemoglobin, the oxygen carrying component of the red blood cell in the human body. Treatment for thalassemia depends on patient condition, usually the medical team take an action due to subtype of the disorder, but may include treatment for anemia, blood transfusions, and treatment for the effects of blood transfusions, such as iron overload.

Patients with Thalassemia who getting treatment by regular Blood transfusions system commonly they have serious situation for life-threatening due too anemia. There are two form of Beta Thalassemia that need to get treatment by regular Blood transfusions; Thalassemia Intermedia (TI) and Thalassemia major (Cooley's anemia). This treatment gives a patient healthy red blood cells with normal hemoglobin.

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